[HTML][HTML] Exogenous recombinant human insulin-induced severe hypersensitivity reaction precipitating hyperglycemic crisis: A clinical conundrum

KU Lijesh, RD Gupta, M SenthilRaja… - Journal of Family …, 2020 - journals.lww.com
skin biopsy showing evidence of insulin hypersensitivity. He was desensitized to insulin
according to Heinzerling et al. insulin … , latex, or cresol. Subcutaneous injections compared to …

Insulin Therapy:“When Saviour Turns Hostile”

DSMVH Nagarajappaa, SOSSM Srinivasc, R Palanya - 2022 - karger.com
… Additives in insulin preparations, such as protamine, zinc, and cresol, have been shown
to … Severe adverse cutaneous reaction to insulin due to cresol sensitivity. Contact Dermatitis. …

[HTML][HTML] Insulin Therapy:“When Saviour Turns Hostile”

D Soodhana Mohan, V Hebbal Nagarajappa… - Dubai Diabetes and …, 2022 - karger.com
… She had no known drug or food sensitivities. … Additives in insulin preparations, such as
protamine, zinc, and cresol, … Because the skin lesions in our patients were caused by the injection …

Delayed-type Hypersensitivity Reaction to Glargine and Biphasic Isophane Human Insulin in a Filipino Patient with Type 2 Diabetes Mellitus: A Practical Approach to …

CSC Tan-Lim, AS de Peralta… - Acta Medica …, 2022 - actamedicaphilippina.upm.edu.ph
… This report illustrates a case of an insulin hypersensitivity reaction successfully diagnosed …
Severe adverse cutaneous reaction to insulin due to cresol sensitivity. Contact Dermatitis 2006…

Insulin, not the preservative m-cresol, instigates loss of infusion site patency over extended durations of CSII in diabetic swine

MR Swinney, AL Cox, ED Hawkins, J Xue… - Journal of …, 2021 - Elsevier
… that they either severely over-dosed m-cresol, 27 evaluated … focusing on the dermal and
subcutaneous tissues, due to their … rat insulin kit recognizes human insulin with higher sensitivity

[HTML][HTML] Case Report: Insulin hypersensitivity in youth with type 1 diabetes

EH Alkhatib, JB Grundman, AM Adamusiak… - Frontiers in …, 2023 - frontiersin.org
severity and presentation of insulin hypersensitivity reactions along … meta-cresol, but the
localized skin reactions persisted. … Skin intradermal testing is more sensitive, but lacks specificity…

Intranasal insulin

M Hallschmid - Journal of neuroendocrinology, 2021 - Wiley Online Library
… Levemir) that contain m-cresol (meta-cresol), an excipient with … idea that the sensitivity to
the anorexigenic impact of insulin is … of IN insulin on fear extinction turned out to pertain to skin

[PDF][PDF] Delayed hypersensitivity reactions caused by drug excipients: a literature review

ML Caballero, S Quirce - J Investig Allergol Clin Immunol, 2020 - jiaci.org
… Contact, systemic, and irritant cutaneous reactions have been … Drug intolerance reaction
to insulin therapy caused by … hypersensitivity reaction to the meta-cresol component of insulin

In vivo Study of Insulin-loaded Microemulsion Topical gel with Aloe vera for the Treatment of Dermatologic Manifestation of Diabetes

T Chakraborty, S Gupta, V Saini - Research Journal of …, 2020 - indianjournals.com
… the stability of injectable insulin formulation but these causes serious adverse effects (allergic …
Severe adverse cutaneous reaction to insulin due to cresol sensitivity. Contact Dermatitis. …

[PDF][PDF] Subcutaneous Injectable Drugs Hypersensitivity and Desensitization

S Bavbek, MJ Lee - academia.edu
related to insulin with brief discussion of ISRs. … Cresol also has been used for skin prick
testing at 1.5 to 3 mg/mL.If there is a suspicion for latex sensitivity, latex-specific IgE and/or skin